DIRS.INFO The most relevant business & tech news

☆ Genes known to increase the risk of Alzheimer’s may actually be an inherited form of the disorder, researchers say
▼ + stars: | 2024-05-06 | by ( Brenda Goodman | ) edition.cnn.com time to read: +10 min

Among people diagnosed with Alzheimer’s, researchers recognize familial forms of the disease and sporadic cases. This shifting appreciation of inherited risk, researchers say, is due to a better understanding of the role of a fourth gene that carries the blueprints to make a lipid-carrying protein called apolipoprotein E, known as APOE. One known as APOE2 is thought to be protective against the development of Alzheimer’s disease. They also compared people with two copies of APOE4 to people with other inherited forms of the disease — early-onset autosomal dominant Alzheimer’s disease (ADAD) and Down syndrome-associated Alzheimer’s disease (DSAD). Gene testing isn’t currently recommendedIt is also likely to change how people who carry the APOE4 gene are diagnosed and treated.

Persons: APOE4, ”, Dr, Juan Fortea, Sant, Fortea, Charles Bernick, Bernick, Alzheimer’s wasn’t, isn’t, they’re, ” Fortea, Sanjay Gupta, Reisa Sperling, “, ” Sperling, ” Dr, Sterling Johnson, Johnson Organizations: CNN, Nature, National Alzheimer’s Coordinating, Neurology, Hospital de, Cleveland Clinic Lou, Brain Health, CNN Health, Alzheimer’s Research, Brigham, Women’s, Alzheimer’s, University of Wisconsin Locations: Alzheimer’s, Spain, United States, Santa, Barcelona, Wisconsin

Read previewIt appears Elon Musk and Grimes are getting along again after the former couple sued each other last year, kicking off a contentious legal battle over the three children they share. Grimes shared a clip from the video game "Cyberpunk 2077: Phantom Liberty" in which a character she voices performs a song onstage and appears suspended in a holographic spider web. Musk sued the musician on September 7, 2023, to "establish the parent-child relationship" with the children. Related storyOn September 29, 2023, Grimes sued Musk, asking for primary physical custody and joint legal custody of their three kids. AdvertisementNeither Musk nor Grimes, or their representatives, have commented publicly on the custody battle.

Persons: —, Elon Musk, Grimes, Musk, didn't, Matteo Milleri, Anyma, Milleri Organizations: Service, Business, Lone Star State Locations: Texas, California, Italian, Belgium, Indio , California

☆ Billy Guyton: First New Zealand professional rugby union player confirmed to have died with CTE
▼ + stars: | 2024-03-18 | by ( Issy Ronald | ) edition.cnn.com time to read: +5 min

CNN —A former professional rugby union player, who who died in 2023 at the age of 33, has become the first in New Zealand to be formally diagnosed with chronic traumatic encephalopathy (CTE) – the neurogenerative disease associated with repeated head trauma. Billy Guyton died of a suspected suicide last year, CNN affiliate Radio New Zealand (RNZ) reported, and his family subsequently donated his brain to Auckland’s Neurological Foundation Human Brain Bank which made the CTE diagnosis. CNN has contacted New Zealand Rugby for comment. Around the world, players are grappling to deal with the impact of head injuries sustained during their rugby careers. In the UK, some 450 current and former rugby players have now joined lawsuits to take legal action against global governing body World Rugby and the national governing bodies of England and Wales, the Rugby Football Union (RFU) and the Welsh Rugby Union (WRU), Rugby Football League Limited, International Rugby League Limited and British Amateur Rugby League Association.

Persons: CNN —, Billy Guyton, Maurice Curtis, John, RNZ, “, ”, Billy, That’s, Australia – Guyton, ” John Guyton, Michael Buckland, Curtis Organizations: CNN, rugby, Radio New Zealand, Neurological, Brain, Auckland Brain Bank, Super Rugby, Australia, Nelson Weekly, New Zealand Rugby, Australian Sports Brain Bank, World Rugby, Rugby Football Union, RFU, Welsh Rugby Union, WRU, Rugby Football League Limited, International Rugby League Limited, British Amateur Rugby League Association . Lawyers, University of Glasgow, Boston University, University of Sydney, Prevention, Befrienders Locations: New Zealand, Auckland, England, Wales

☆ Emma Heming Willis says husband Bruce’s life is still filled with joy
▼ + stars: | 2024-03-04 | by ( Lianne Kolirin | Jack Guy | ) edition.cnn.com time to read: +3 min

CNN —Bruce Willis’ wife has hit out at an online report that “there is no more joy” in her husband’s life. Emma Heming Willis said in a video posted to her Instagram profile on Sunday that she had been “clickbaited” by a headline “to do with my own family.”Appearing angry and frustrated, Heming Willis said she had been “triggered” by the story, which she came across on Sunday morning. Love is a beautiful thing ❤️ Wishing you all a Happy Valentine’s Day 🫶🏽 Emma Heming Willis/InstagramIn an interview last year, Heming Willis admitted that the diagnosis had been tough on her husband, herself and their two daughters. “What I’m learning is that dementia is hard,” Heming Willis told Hoda Kotb on the Today show on NBC. And that is no different for Bruce or myself or our girls.”That said, in a written message accompanying her video, Heming Willis explained that there was a lot more to the family’s situation than many headlines suggest.

Persons: Bruce Willis ’, Emma Heming Willis, ”, Heming Willis, Willis, “ Organizations: CNN, Alzheimer’s Research Locations: FTD

☆ Apparently Healthy, but Diagnosed With Alzheimer’s?
▼ + stars: | 2024-03-04 | by ( Paula Span | ) www.nytimes.com time to read: 1 min

Determining whether someone has Alzheimer’s disease usually requires an extended diagnostic process. A doctor takes a patient’s medical history, discusses symptoms, administers verbal and visual cognitive tests. or a spinal tap — tests that detect the presence of two proteins in the brain, amyloid plaques and tau tangles, both associated with Alzheimer’s. All of that could change dramatically if new criteria proposed by an Alzheimer’s Association working group are widely adopted. Its final recommendations, expected later this year, will accelerate a shift that is already underway: from defining the disease by symptoms and behavior to defining it purely biologically — with biomarkers, substances in the body that indicate disease.

Organizations: Alzheimer’s Association

☆ The Authorities Don’t Need A.I. When Your Neighbors Will Narc on You
▼ + stars: | 2024-02-28 | by ( Annalee Newitz | ) www.nytimes.com time to read: +1 min

Prisoners living under these towers never know whether the guards are looking at them, but they have to assume that they are being watched. This setup, Foucault explained, is a powerful metaphor for modern civilization: Our lives are circumscribed by a fear that invisible authorities have us in their sights. Two new books about state surveillance in the 21st century, one focused on China and the other on the United States, make it clear that Foucault was right. In China, as Minxin Pei explains in “The Sentinel State,” a centralized Communist government uses new tech to extend a centuries-old system of bureaucracy that rewards intelligence gleaned from informants and spies. And in the United States, Byron Tau’s “Means of Control” documents how a federal democracy formed shady alliances with private companies to collect data on its citizens.

Persons: Byron Tau, Minxin Pei, Michel Foucault, ”, Jeremy Bentham, Foucault, Byron Tau’s “ Organizations: Alliance of Tech, American Surveillance, Byron Tau THE, “ The Sentinel State, Communist Locations: China, French, United States, “

☆ How to fight dementia, according to neurologists
▼ + stars: | 2024-02-12 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +17 min

What about diabetes, cancer, thyroid disease, high blood pressure or heart disease? Some of the questions might seem unexpected to those who don’t write about brain health. However, my risk of developing vascular dementia, the second most common type after Alzheimer’s disease, is elevated. "Such spikes cause brain inflammation, disrupt brain metabolism and increase shrinkage of the thinking part of the brain," Isaacson said. The National Institute on Aging currently supports nearly 500 active clinical trials on Alzheimer’s disease and related dementias.

Persons: Louise Dittner, Krysta, Ryan LaMotte, It’s, ”, Natalia Rost, “, Rost, ” Rost, Richard Isaacson, ” Isaacson, mockingbird …, birthed, it’s, I’ve, Isaacson, Sandee LaMotte Organizations: CNN, Comprehensive, Massachusetts General Hospital, Harvard Medical School, American Academy of Neurology, Boca Raton, Weill Cornell Medicine, Presbyterian, Mayo Clinic, Volunteers, Alzheimer’s, National Institute on Aging, National Institutes of Health Locations: Massachusetts, Boston, neonatologists, Florida, United, New York, New York City, Nature

☆ Host nation Ivory Coast continues miraculous run to AFCON final to set up a matchup against Nigeria
▼ + stars: | 2024-02-11 | by ( Samuel Joseph | Sam Joseph | ) edition.cnn.com time to read: +5 min

The host nation is seeking its third AFCON title, while Nigeria is looking to lift the trophy for the fourth time. ET on Sunday and will take place at the Alassane Ouattara Stadium in Abidjan, Ivory Coast. Ivory Coast midfielder Ibrahim Sangare (L) fights for the ball with DR Congo's Simon Banza. Against Mali, Ivory Coast pulled off yet another great escape, grabbing a last-minute equalizer. Nigeria goalkeeper Stanley Nwabali made two saves and striker Kelechi Iheanacho netted the deciding penalty to send Nigeria into the final.

Persons: Ouattara, Ivory, Les Éléphants, Jean, Louis Gasset, Emerse Faé, Ibrahim Sangare, DR Congo's Simon Banza, Franck Fife, Faé, Franck Kessié, Simon Adingra, Sébastien Haller, Ivory Coast's, Sia Kambou, William Troost, Ekong, Victor Osimhen, Osimhen, Percy Tau, Teboho Mokoena, Issouf Sanogo, Grant Kekana, Stanley Nwabali, Kelechi Iheanacho Organizations: CNN, Africa, of Nations, beIN Sports USA, DR Congo, Guinea, Equatorial, Coast, Ivory, DR Congo's, Getty, Senegal, Against, Ivory Coast, Nigeria, Super Eagles, South Africa Locations: Ivory Coast, Nigeria, Ivory, Abidjan, South Africa, Bissau, Equatorial Guinea, AFP, Against Mali, Europe, AFCON, Cameroon, Angola, Africa

☆ Healthy living may battle cognitive decline even with signs of dementia in the brain, study suggests
▼ + stars: | 2024-02-05 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +6 min

CNN —Living a healthy lifestyle with a focus on a nutritious diet, regular exercise, minimum alcohol consumption and other healthy habits can help keep your brain sharp into old age, doctors say. But what if your brain already has signs of beta amyloid or tau — two of the hallmark signs of Alzheimer’s and other brain pathologies? Will a healthy lifestyle still protect you from cognitive decline? Not everyone who has signs of Alzheimer’s or vascular dementia goes on to develop cognitive issues, but many do. In fact, “a higher healthy lifestyle score was associated with better cognition even after accounting for the combined burden of brain pathologies,” according to Yaffe and Leng.

Persons: ”, Dr, Klodian, Richard Isaacson, “, Isaacson, wasn’t, —, Kobus, Lewy, Yue Leng, Kristine Yaffe, Yaffe, San Francisco Weill Institute for Neurosciences . Leng, Leng, it’s Organizations: CNN, Rush Institute, Healthy Aging, Rush University, “, University of California, San Francisco Weill Institute for Neurosciences . Locations: Chicago, Florida, San

☆ Dementia and sport: These rugby players represented their country in their 20s, by their 40s, they had early onset dementia
▼ + stars: | 2024-02-05 | by ( Amy Woodyatt | ) edition.cnn.com time to read: +17 min

Popham’s wife, Mel, would have a conversation with her husband and an hour later he would have “no recollection,” he tells CNN Sport. Richard Boardman, the lawyer representing the claimants, told CNN Sport that this is causing an “existential threat” to the game. “As far as the brain is concerned, it doesn’t matter what sport is played,” Michael Grey, a neuroscientist at the University of East Anglia, told CNN Sport. Nowinski, a WWE wrestler turned neuroscientist, told CNN Sport that head injury protocols need to go beyond treating concussion. The paper, which looked at 412 Scottish former international male rugby players aged 30 and above and 1,236 members of the public who had been matched for age, sex and socioeconomic status, found that the rugby players’ risk of a dementia diagnosis over time was just over twice as high.

Persons: Alix Popham, Mel, ”, Popham, ” Popham, I’ve, Alix Popham of Wales, Pat Riordan of, Stu Forster, Lenny Woodard, Woodard, “, “ I’d, I’d, ” Woodard, Brook Joyner, Richard Boardman, ” Michael Grey, Chris Nowinski, Scott McIntyre, Nowinski, ” Ann McKee, ” Boardman, Roger Goodell, University of East Anglia Boardman, Grey, –, ” Steve Borthwick of, Alun Wyn Jones, Paul Harding, ” Grey, McKee, it’s, aren’t, we’re, shouldn’t, weren’t, ” Alix Popham Organizations: CNN, CNN Sport, rugby, Rugby, Alix Popham of Wales offloads, Pat Riordan of Canada, Wales, Getty, World Rugby, Rugby Football Union, RFU, Welsh Rugby Union, WRU, Springer, University of East, National Football League Players, Wrestling Entertainment, WWE, Washington Post, Boston University CTE Center, British Medical, Exercise, NFL, NFL.com, University of East Anglia, RBS, Nations, University of Glasgow, Boston University, University of Sydney, Scottish, ’, “ Rugby, England Rugby, Boston University’s CTE, CTE Locations: France, Wales, England, Canada, Nantes, Europe, University of East Anglia, American, Woodward, Boston

☆ Factories in developing Asia may have seen the worst of manufacturing slump
▼ + stars: | 2024-02-01 | by ( Clement Tan | ) www.cnbc.com time to read: +3 min

Photographer: Linh Pham/Bloomberg via Getty Images Bloomberg | Bloomberg | Getty ImagesMost developing economies in Asia might have left the worst of the broad manufacturing slowdown behind in 2023, according to a series of private surveys released Thursday. South Korea's S&P manufacturing purchasing managers' index recorded its first expansionary reading since June 2022 at 51.2 in January, up from 49.9 in December. "The health of the South Korean manufacturing sector registered a renewed improvement at the start of 2024. Growth was reportedly reflective of increased domestic and international orders, particularly for new products," Bhatti added. These private PMI surveys are typically seen as one of several leading indicators of economic activity in the respective economies.

Persons: Linh Pham, Usamah Bhatti, Bhatti, Annabel Fiddes Organizations: Wind Corp, Vung, Renewables, International Energy Agency, Bloomberg, Getty Images Bloomberg, Getty, P Global Market Intelligence, Vietnam, ASEAN, PMI, International Monetary Fund, IMF, " Companies Locations: Tan Thanh, Ba, Vung Tau Province, Vietnam, Asia, China, Taiwan, Malaysia, Thailand

☆ Biogen drops controversial Alzheimer's drug Aduhelm to focus on Leqembi, experimental treatments
▼ + stars: | 2024-01-31 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +2 min

Biogen on Wednesday said it will discontinue the sale and development of its older and highly controversial Alzheimer's drug Aduhelm to refocus the company's efforts to treat the memory-robbing disease. The biotech company will focus on rolling out Leqembi, a newly approved Alzheimer's drug it developed with Japanese drugmaker Eisai . The U.S. Food and Drug Administration greenlit Aduhelm in 2021 under a program that fast-tracks promising treatments. The company said it will redistribute a large portion of the resources associated with Aduhelm to the rest of its Alzheimer's drug portfolio. Among the other Alzheimer's drugs Biogen has in development is BIIB080, which targets a toxic protein called tau in the brain.

Persons: Biogen, Aduhelm Organizations: U.S . Food, Drug Administration, CNBC PRO Locations: U.S, Swiss

☆ Rare cases of possible Alzheimer’s transmission uncovered in recipients of discontinued medical treatment
▼ + stars: | 2024-01-29 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +9 min

All five adults had growth hormone deficiency as children and received pituitary growth hormones prepared in a specific way from cadavers. The treatment approach was discontinued after cases of a rare brain disorder called Creutzfeldt-Jakob disease were found to be associated with the administration of contaminated human growth hormone from cadavers. Although Alzheimer’s is not a prion disease, some separate research suggests that the two proteins that are hallmarks in Alzheimer’s disease — amyloid beta and tau — behave like prions. “This study suggests that in very rare circumstances Alzheimer’s disease may be transmitted between humans via human growth hormone from deceased donors. “I’m also intrigued by how these results may inform potential therapeutic targets and strategies in the future,” Isaacson said, regarding Alzheimer’s disease.

Persons: John Collinge, Jakob, Creutzfeldt – Jakob, Alzheimer’s, ” Collinge, ’, –, ” Dr, Susan Kohlhaas, ” Kohlhaas, “ It’s, Dr, Richard Isaacson, ”, Isaacson, “ I’m, ” Isaacson, “, Gargi Banerjee, ” Banerjee, James Galvin, Sanjay Gupta, ” Galvin, Lewy Organizations: CNN, Nature, University College London Institute, University College London, National Hospital for Neurology, Neurosurgery, Alzheimer’s Research, Science Media, Comprehensive, Brain Health, University of Miami Health, CNN Health Locations: United Kingdom, United States, United, Florida, UHealth, Creutzfeldt

☆ TikTok's Lunden and Olivia Stallings are straight people's favorite lesbian couple. What do they owe queer fans?
▼ + stars: | 2024-01-25 | by ( Kate Taylor | ) www.businessinsider.com time to read: +29 min

Lunden and Olivia told me their mission as influencers was to "represent and inspire others to be their authentic self." Advertisement"I did feel represented by them," Asia said, but the tweets "showed me that they are still white women." "We are especially confident in our sexuality and the way that we feel and who we are," Olivia told me. Lunden and Olivia told me they want to advocate for all LGBTQ+ people, including those who don't look like them. It's a chance, the couple told me, to combat the hate and negativity LGBTQ+ parents face.

Persons: Lunden Stallings, Olivia Bennett, Monique Lhuillier, Lunden, Taylor Swift, Stallings, David Yurman, preppy, Olivia, TikTok, Kendrick Brinson, who's, you've, Madison Mathews, sunnies, peck, they'd, Brooklynites, Remington, Zeta Tau, Olivia DMed Lunden —, Justin Bieber, snapbacks, haven't, Lunden's, Ellie Goulding's, Olivia couldn't, Caroline Bayne, Lunden's TikTok, Zara, Mercedes, Sophie, It's, Jackie J, Jackie, There's, Bud Light, Dylan Mulvaney, influencers, They've, KenzKustomz, Krysten Stein, Black influencers, Stein, Hill, millennials Organizations: Naylor, People, Business, Alabama, Chevrolet, New York Post, Daily Mail, Madison, University of Central, Jacksonville State University, Zeta Tau Alpha, University of Alabama's, University, Minnesota, BI, Braves, Rover, Pride, Nielsen, Saks, University of Illinois Locations: Roswell , Georgia, Asia, Olivia, Charleston, LoveShackFancy, Powder Springs , Georgia, Atlanta, Blytheville , Arkansas, University of Central Arkansas, Alabama, Roswell, Austin, RushTok, Alpharetta, Charleston , South Carolina, Southern, Publix, Fayetteville , Arkansas, University of Illinois Chicago

☆ New blood test that screens for Alzheimer’s may be a step closer to reality, study suggests
▼ + stars: | 2024-01-22 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +11 min

Alzheimer’s disease, a brain disorder that affects memory and thinking skills, is the most common type of dementia, according to the National Institutes of Health. “A blood test being negative speeds up the investigation for other causes of the symptoms and this is just as important,” Ashton said. Isaacson, who has researched blood biomarkers in people with no or minimal cognitive complaints, likened testing blood samples for signs of Alzheimer’s disease to how people undergo routine blood tests for high cholesterol. It is possible that currently available treatments for Alzheimer’s disease would work better in those diagnosed early in this way,” he said. The combination of a simple screening test with an effective treatment for Alzheimer’s disease would have a dramatic impact for individuals and for society.”

Persons: ” Nicholas Ashton, Ashton, ”, Kaj Blennow, Henrik Zetterberg, antiamyloid, immunoassay, ” Ashton, Richard Isaacson, ” Isaacson, Isaacson, ‘, “, Dr, Sanjay Gupta, David Curtis, ” Curtis Organizations: CNN, University of Gothenburg, National Institutes of Health, Quest Diagnostics, Alzheimer’s, Alzheimer’s Association, Get CNN, CNN Health, University College London, Science Media Locations: Sweden, United States, Wisconsin, Pau, Florida

☆ I kicked my son out during the peak of his drug addiction. He recovered, and I'm grateful for the years I didn't think I'd get with him.
▼ + stars: | 2023-12-27 | by ( Jennifer Cannon | ) www.businessinsider.com time to read: +5 min

My son started smoking marijuana in high school and things quickly escalated to heroin. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . The 10-year detour his life took after high school spanned all things concerning whether he would make it out of this alive. Standing at the kitchen sink one summer morning in 2010, the warm prickle of hives took shape down my legs. AdvertisementWhen I first learned Bryant was smoking marijuana, I thought, "he's in high school."

Persons: I'm, what's, —, Bryant, I'd, Cesar Deleon, I've, Weeks Organizations: Service, University of North, Engineers, Anonymous, FAU, Tau Beta Pi Locations: Florida, California, University of North Florida, Lake Worth

Grimes alleged Elon Musk spent less than half his time in 2023 in Texas, in recent legal filings. Musk still spends two to three days a week in California, Grimes alleged. AdvertisementElon Musk — who moved Tesla's headquarters from California to Texas in 2021— has been spending less than half his time in the Lone Star State, Grimes alleged in recent legal documents. Musk quietly sued Grimes in Texas court in September to establish a "parent-child" relationship with the kids. While Grimes has said the child was with Musk in Texas over her objection, the details around the arrangement, and how she responded, are unclear.

Persons: Grimes, Elon Musk, Musk, —, Elon, Claire Boucher, X, Christopher Melcher, Walzer Melcher, Tesla, Peter Walzer Organizations: Service, Lone Star State, Tau, Business, Musk, Street Journal, Montessori, Twitter, SpaceX Locations: Texas, California, Austin , Texas, Austin, Hawthorne , California, Brownsville , Texas, Bay Area . Texas, Starbase, SpaceX's, Boca Chica , Texas, Snailbrook, Boring, Bastrop , Texas, State, San Francisco, Palo Alto

☆ Elon Musk says his kids' safety is at risk unless a Texas judge restricts access to his custody battle with Grimes
▼ + stars: | 2023-12-02 | by ( Erin Snodgrass | Grace Kay | ) www.businessinsider.com time to read: +7 min

Elon Musk filed new documents in Texas court asking a judge to restrict access to his custody battle. Attorneys for Musk want a judge to issue a protective order before he agrees to sit for a deposition. Musk also asked a judge to suspend public access to documents in the case, arguing the potential risk to his children outweighs any public interest in the high-profile custody battle. AdvertisementMusk was first to strike, however, quietly suing Grimes in Texas court in September to establish a "parent-child" relationship with the kids. AdvertisementA protective order would guarantee the information Musk reveals during a deposition remains private and inaccessible to the public, Melcher added.

Persons: Elon Musk, —, Grimes, Musk, Claire Boucher, X, Grimes didn't, Christopher Melcher, Walzer Melcher, Melcher, Elon, Chesnot, Frazer Harrison, countersued, CHANDAN KHANNA, Jack Sweeney, Sweeney, he'd, Bob Iger Organizations: Musk, Service, Business, Tau, BI, Elon, Getty, Circuit, SpaceX, Twitter, Sweeney, Summit, Disney Locations: Texas, California, Americas, Austin , Texas, Ukraine

☆ Bigger belly in 40s and 50s linked to early signs of Alzheimer’s disease
▼ + stars: | 2023-11-20 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +8 min

CNN —Inflammation from belly fat may be linked to the early stages of Alzheimer’s disease decades before symptoms begin, new research has found. “That’s important because brain atrophy is another biomarker of Alzheimer’s disease,” Raji said. “These are people who, if they do develop Alzheimer’s disease, it won’t happen for another 20 or 25 more years. “Regardless of weight, people should find out if they have hidden visceral fat,” Raji said. Visceral fat ‘easier to lose’There’s good news: Visceral fat responds well to diet and exercise, Raji said.

Persons: “, ”, Richard Isaacson, Isaacson, Cyrus Raji, St . Louis, ” Raji, Dr, Mahsa, Raji, ” Isaacson, It’s Organizations: CNN, Washington University School of Medicine, Radiology Society, Cleveland Clinic, Mayo Clinic Locations: Florida, St .

☆ Researchers return to Alzheimer's vaccines, buoyed by recent drug success
▼ + stars: | 2023-11-20 | by ( Julie Steenhuysen | ) www.reuters.com time to read: +6 min

The renewed interest in Alzheimer's vaccines follows a promising first attempt more than 20 years ago that was abandoned after 6% of study volunteers developed life-threatening brain inflammation known as meningoencephalitis. Dr. Reisa Sperling, an Alzheimer's researcher at Mass General Brigham in Boston, said she believes vaccines will play an important role as researchers look to prevent Alzheimer's. She is considering vaccines for her next study in asymptomatic people with Alzheimer's proteins in their blood, but not enough to register on brain scans. Alzheimer's vaccines are still in the early stages and will require large, years-long trials to show they work. Generating a strong immune response is critical for such vaccines, which would typically be given to older individuals with weaker immune systems, he said.

Persons: Brian Snyder, Eli Lilly's, Reisa Sperling, Brigham, “, ” Sperling, Walter Koroshetz, Mei Mei Hu, Vaxxinity, Hu, Michael Rafii, Rafii, Andrea Pfiefer, Johnson, Prothena, Gene Kinney, Julie Steenhuysen, Caroline Humer, Bill Berkrot Organizations: Alzheimer Research, Brigham, Women's, REUTERS, Rights, U.S . Food, Drug Administration, Mass, National Institutes of Health, UB, University of Southern, Johnson, Bristol Myers Squibb, Thomson Locations: Boston , Massachusetts, U.S, Boston, Taiwan, University of Southern California

☆ Sweet spot for HRT may reduce dementia risk by nearly a third, study says
▼ + stars: | 2023-11-02 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +8 min

Just how harmful or helpful hormone replacement therapy may be also depends on the type of hormones that are prescribed, especially at older ages. Estrogen-only hormone therapy can be prescribed if the uterus has been removed via hysterectomy. Scientists are developing a new generation of hormone replacement called selective estrogen receptor modulator, or SERM. Scientists are working on new forms of hormone replacement therapy that go directly to the brain, thus making them safer for menopausal women. In addition, some women are not candidates for hormone replacement therapy, perhaps due to family history, heart conditions or clotting disorders.

Persons: hasn’t, “, ”, Lisa Mosconi, Mosconi, Richard Isaacson, ” Isaacson, gynecologists, midlife, ” Mosconi Organizations: CNN, Weill Cornell Medicine, “ Locations: New York City, midlife, Florida

☆ Elon Musk paraded his son X at a Formula One event in Texas in the middle of a custody battle with Grimes over where the boy primarily lives
▼ + stars: | 2023-10-25 | by ( Lauren Steussy | Kelsey Vlamis | Erin Snodgrass | ) www.businessinsider.com time to read: +4 min

Elon Musk's current custody battle with Grimes hinges on where his children with the musician live. At a Formula 1 event in Texas, Musk was pictured waving to the crowd with his son X on his shoulders. AdvertisementAdvertisementTesla CEO Elon Musk made an appearance at Sunday's F1 race in Austin, Texas, with his son X perched on his shoulders. The 3-year-old is at the center of a parental rights battle between Musk and his sometimes-partner, musician Grimes. X, meanwhile, is "only absent from California over [Boucher's] objection," according to Grimes' October 6 request for Musk's case to be thrown out, previously obtained by Insider.

Persons: Elon Musk's, Grimes, Musk, X, —, Elon Musk, Claire Boucher, Musk's Cybertruck, nannies, Peter M, Walzer Melcher, Grimes didn't Organizations: Service, Tau, SpaceX, Mercedes, Musk Locations: Texas, Austin , Texas, California, Musk's

The Alzheimer's drug LEQEMBI is seen in this undated handout image obtained by Reuters on January 20, 2023. Eisai/Handout via REUTERS/File Photo Acquire Licensing RightsBOSTON, Oct 25 (Reuters) - An injected version of Eisai (4523.T) and Biogen's (BIIB.O) Alzheimer's drug Leqembi works as well as the current intravenous version at removing toxic brain plaques, according to an analysis presented by Eisai on Wednesday. The Japanese drugmaker's review compared data for 72 patients with early Alzheimer's given Leqembi by subcutaneous injection to prior pivotal trial results from 898 patients who received the drug by infusion. Blood concentration levels of the drug were 11% higher with subcutaneous Leqembi than the IV version. Roll-out of IV Leqembi, which has an annual list price of $26,500, has been slow.

Persons: Eisai, Leqembi, ”, Eric Reiman, Priya Singhal, Biogen, Michael Irizarry, Alzheimer's, Julie Steenhuysen, Deena Beasley, Bill Berkrot, Leslie Adler Organizations: Reuters, REUTERS, Rights, Banner Alzheimer's Institute, ARIA, Thomson Locations: Handout, Boston, Los Angeles

☆ Doubts abound about a new Alzheimer’s blood test
▼ + stars: | 2023-10-18 | by ( Judith Graham | ) edition.cnn.com time to read: +10 min

The Quest Diagnostics blood test, AD-Detect, measures elevated levels of amyloid-beta proteins, a signature characteristic of Alzheimer’s. But Alzheimer’s researchers and clinicians aren’t convinced the Quest test is backed by sound scientific research. Though blood tests for Alzheimer’s are likely to become common in the years ahead, the Alzheimer’s Association said it’s premature to offer a test of this kind directly to consumers. Because the science behind blood tests for Alzheimer’s is still developing and because “patients may not really understand the uncertainty of test results,” Edelmayer said, the Alzheimer’s Association “does not endorse the use of the AD-Detect test by consumers.”Quest’s blood test is one of several developments altering the landscape of Alzheimer’s care in the United States. The bottom line: Before taking a test, “older adults need to ask themselves, ‘Why do I want to know this?

Persons: aren’t, Alzheimer’s, Michael Racke, ”, there’s, Suzanne Schindler, St . Louis, That’s, ” Schindler, Racke, Meera Sheffrin, —, Rebecca Edelmayer, ” Edelmayer, Eric Widera, Dr, Sanjay Gupta, Emily Largent, ’ ”, Munro Cullum Organizations: Health, Diagnostics, Alzheimer’s Association, Quest, University of Michigan, International Conference, Washington University School of Medicine, Senior, Stanford Healthcare, The University of Michigan, FDA, National Institute, Aging, University of California, Get CNN, CNN Health, University, Pennsylvania’s Perelman, of Medicine, HIPAA, University of Texas Southwestern Medical Center, Kaiser Health, KFF Locations: U.S, San Diego, St ., United States, San Francisco

Most of the school burned down, but its leaders quickly got classes up and running at Sacred Hearts Mission Church 10 miles (16 kilometers) away. Sacred Hearts and other private schools across the state took in displaced public school students, such as Cuaresma, while offering a year of free tuition. Other students bused more than 45 minutes away to public schools on the other side of Maui or opted for remote classes. Debbie Tau’s two children won’t return to their Lahaina schools because she also is worried the air isn’t safe. Patrick Williams said the first time he saw his son Kupaʻa praying at Sacred Hearts reminded him of his own childhood in Mississippi.

Persons: ”, Cailee Cuaresma, “ I’m, Cuaresma, Tonata Lolesio, “, Lahaina , King Kamehameha III, Nāhiʻenaʻena, Tiffany Teruya, Puʻuwai, Debbie Tau’s, Patrick Williams, ’ ” Williams, Williams, Gabby Suzik, Suzik, ” Suzik, Charlene Ako, Ako, Maile Organizations: Lahainaluna High, Sacred Hearts School, Hearts Mission, Hearts, Workers, Assistance Dogs, Lahaina, Maui Preparatory Academy, Lahaina’s, Maui Prep Locations: LAHAINA, Hawaii, Maui, Lahaina, Lahaina , King, Kihei, COVID, Mississippi, Asuncion, Waiola

Search resuls for: "Tau"

25 mentions found